Toward precise arterial input functions derived from DCE‐MRI through a novel extracorporeal circulation approach in mice
نویسندگان
چکیده
منابع مشابه
Toward local arterial input functions in dynamic contrast-enhanced MRI.
PURPOSE To present a method for estimating the local arterial input function (AIF) within a dynamic contrast-enhanced MRI scan, based on the alternating minimization with model (AMM) method. MATERIALS AND METHODS This method clusters a subset of data into representative curves, which are then input to the AMM algorithm to return a parameterized AIF and pharmacokinetic parameters. Computer sim...
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Introduction: Tracheal chondrosarcoma (TCS) is a rare malignancy, with only 19 cases described in the literature to date. Case presentation: Herein, we presented the third-largest TCS with such an airway compromise that neither orotracheal intubation nor jet ventilation or even tracheostomy was possible. So, extracorporeal circulation was needed to excise the tumor in a one-stage procedure. Th...
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We would like to refer to the recently published article by Aboud et al. [1] regarding negative venous line pressures and increased arterial air bubble count during minimized extracorporeal circulation (MECC). We think that there are several flaws in this paper. Recent studies have mainly focussed on gaseous microemboli (GME). Approaches are manifold, using arterial line filters, or additionall...
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dceMRI is becoming a key modality for tumour characterisation and monitoring of response to therapy, because of the ability to identify the underlying tumour physiology. Pharmacokinetic (PK) models relate the contrast enhancement seen in dceMRI to physiological parameters but require accurate measurement of the AIF, the time-dependant contrast concentration in blood plasma. In this study, a nov...
متن کاملA Novel Minimal Invasive Mouse Model of Extracorporeal Circulation
Extracorporeal circulation (ECC) is necessary for conventional cardiac surgery and life support, but it often triggers systemic inflammation that can significantly damage tissue. Studies of ECC have been limited to large animals because of the complexity of the surgical procedures involved, which has hampered detailed understanding of ECC-induced injury. Here we describe a minimally invasive mo...
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ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2020
ISSN: 0740-3194,1522-2594
DOI: 10.1002/mrm.28214